Welcome to the UK DRI Neuromics Data Explorer - a gateway to a harmonised Omics data visualisation portal for UK DRI research labs under the Glial theme.
This interactive dashboard prototype allows researchers to seamlessly explore and visualise multiomic datasets from various studies, all in one place.
What can you do?- Interactive visualisation: Identify patterns across different studies - generate and share publication-ready plots
- Intra-study analysis: Compare gene expression across datasets within the selected lab
- Multi-modal integration: Compare protein and gene expression levels simultaneously
- Data export: Download filtered results for further analysis
Quick Start Guide
Select laboratory → Choose your selected lab as data source
Pick datasets → Select one or more studies
Search genes → Search for your genes/ proteins of interest
Explore results → Navigate to lab-specific, then omic-specific tab
Visualise & export → View and manipulate plots and download relevant data
Search
Search across multiple gene identifiers, aliases, and protein names.
Useful Visualisations
Interactive heatmaps, volcano plots, and correlation analyses with publication-quality plots
Cross-Platform
Integrate proteomics and transcriptomics data to validate findings across omics layers.
Export Ready
Download filtered datasets and respective statistical results.
Histogram Plots by assay
Histogram plot showing logFC distribution across selected datasets.
PCA Plot by assay
PCA plot showing potential correlations, clustering, and variance between samples and conditions by reduction of multidimensional data.
Violin Plots by assay
Violin plot showing statistical distribution of expression values across selected categories with an overlayed boxplot.
Bar Plots by assay
Barplots showing the gene or protein expression of samples, conditions, etc.
Threshold summaries
Multiple Volcano Plots by Study
Volcano plot showing differentially expressed genes between selected conditions.
Default Behaviour
When gene(s) are selected in the side panel, an asterisk will denote them on the heatmap.
Heatmaps by Study
Comparative hierarchical visualisation of proteins across selected datasets.
Histogram Plots by assay
Histogram plot showing logFC distribution across selected datasets.
PCA Plot by assay
PCA plot showing potential correlations, clustering, and variance between samples and conditions by reduction of multidimensional data.
Violin Plots by assay
Violin plot showing statistical distribution of expression values across selected categories with an overlayed boxplot.
Bar Plots by assay
Barplots showing the gene or protein expression of samples or conditions, etc.
Threshold summaries
Multiple Volcano Plots by Study
Volcano plot showing differentially expressed genes between selected conditions.
Default Behaviour
When gene(s) are selected in the side panel, an asterisk will denote them on the heatmap.
Heatmaps by Study
Comparative hierarchical visualisation of proteins across selected datasets.
Histogram Plots by assay
Histogram plot showing logFC distribution across selected datasets.
DimRed Plots by assay
Plot showing principal components analysis (PCA), t-stochastic neighbour embedding (t-SNE) and uniform manifold approximation and projection (UMAP) analyses on cells, based on the expression data.
Gene Expr Plots by assay
Plot showing gene expression levels overlaid on UMAP coordinates of cells.
Violin Plots by assay
Violin plot showing statistical distribution of expression values across selected categories with an overlayed boxplot.
Bar Plots by assay
Stacked barplots showing the percent composition of samples, groups, clusters, or other groupings.
Threshold summaries
Multiple Volcano Plots by Study
Volcano plot showing differentially expressed genes between selected conditions.
Default Behaviour
If no gene(s) are selected, dot plot will display the first 15 features in no particular order.
Dot Plot by assay
Dot plot shows expression by cluster (or any other category) for several genes simultaneously. Size and colour of each dot represents the proportion of detected expression values and the average expression, respectively, for each feature in each grouping. If no gene(s) are selected, plot will display the first features.
Scater Plot by assay
Scater plot showing the overview of expression for each cell i.e. relative proportion of the library size accounted for by the most highly expressed features for each cell.
Requirement:
Add 2 valid genes to visualise the scatter plot.
Feature Scatter Plot by Study
Scatter plot showing the expression values of two selected features across cell types.
Default Behaviour
If no gene(s) are selected in the side panel's gene's list, the first 4 will be chosen by default.
Violin Plot by Study
Violin plot showing statistical distribution of expression values across selected categories.
HighestExprs Plots
HighestExprs plot showing the highest average expression across all cells, along with their expression in each individual cell.
Default Behaviour
If no gene(s) or cell ID(s) are selected in the side panel or drop-down respectively, the first 30 and 50, respectively, are chosen by default.
Gene Range Selection:
Using Searched Genes:
Heatmap
Heatmap plot showing the expression values for each cell and specified features within the single-cell experiment.